Senior/Principal Scientist, Translational Medicine Mass Spectrometry

Job Description

The Translational Medicine department informs clinical development of novel personalized therapeutics through establishment of biomarker strategies aimed to study biological pathways driving disease and by characterizing the mechanism of action of novel therapeutics. As a key member of the biomarker mass spectrometry laboratory, the ideal candidate will utilize mass spectrometry to explore novel biomarker hypotheses, assist in streamlining existing workflows, and help to drive innovation within the group through improved LC-MS/MS method development.

Experience in clinical proteomics and clinical sample processing is required. Hands-on

experience with maintaining LC and MS instrumentation is also required.

PhD in Analytical Chemistry, Biochemistry, or Biotechnology and successful postdoctoral research training in a related field Minimum of 6 years of hands-on

experience with liquid chromatography and tandem mass spectrometry (LC-MS/MS) approaches, and have excellent troubleshooting capabilities Strong analytical background with fundamentals in assay development, system suitability, and method evaluation

Experience with discovery proteomics approaches (TMT, DIA-MS, SWATH, etc.) and corresponding data analysis tools Knowledge of sample preparation techniques for analysis of biomarkers and other mediators from biological fluids (e.g. plasma, CSF, urine, stool, etc.) A proven ability to analyze and visualize complex datasets using tools like MSstats, Spotfire, R, or Skyline and

experience with standard instrument software such as Analyst or Xcalibur In addition, the candidate should have excellent communication, presentation, and interpersonal

skills, be able to work independently as well as in a team environment, and be willing and eager to learn and train others on new technologies

Pay Rate Range: $60-100/hr.

Salary Will Be Commensurate With

experience

The Planet Group Of Companies Is An

equal opportunity employer. We celebrate

diversity and are committed to creating an inclusive environment for all employees.